Recurrent miscarriage
How UK and US definitions differ, what investigations may be offered, and where to find care and support after repeated loss.
Key points
- RCOG defines recurrent miscarriage as three or more early losses, with investigation after two in some circumstances.
- ACOG defines recurrent pregnancy loss as two or more miscarriages and recommends assessment after two.
- Investigations may look at blood clotting, thyroid function, genetics and the shape of the womb.
- A cause is often not found; support and planning still matter.
After repeated pregnancy losses, you can ask your clinician about tests and support. UK and US guidance use different definitions, but a clinician may offer tests before you meet the formal definition.
The UK and US definitions differ
RCOG defines recurrent miscarriage as three or more first trimester miscarriages. They do not have to happen in a row: there may be a successful pregnancy between losses. The guideline also allows clinicians to recommend investigation after two first trimester miscarriages if they suspect an underlying problem rather than separate chance events.
In the US, ACOG defines recurrent pregnancy loss as two or more miscarriages and recommends a thorough examination and testing after two. Ask your GP or obstetric clinician what assessment is appropriate for your history.
You can ask for support however many losses you have had. At an appointment, you can talk about grief, anxiety and the effect on everyday life alongside questions about physical care.
What the appointment may cover
Your clinician may ask about previous pregnancies and your medical history, and may offer a physical examination. Bring any dates, scan reports or treatment details you already have. A short account is enough to start with. Leave gaps where you are unsure.
Tests look for possible explanations and can include blood tests for antiphospholipid syndrome, known as APS, and thyroid problems. Diabetes testing may be offered when your history suggests it is relevant. A pelvic ultrasound can look at the shape of the uterus, or womb.
Genetic testing may involve pregnancy tissue or, in certain circumstances, you and a partner. RCOG describes offering pregnancy testing at a third or further miscarriage and considering parental tests when tissue cannot be tested or the findings suggest an inherited problem. Ask what a test could tell you and whether it would change care.
What treatment can and cannot promise
Treatment depends on what is found. For people with APS and recurrent miscarriage, a specialist may prescribe aspirin and heparin during pregnancy. These medicines are not a general treatment to try after any loss. Your doctor can explain whether these medicines are suitable for you and how they are prescribed.
Diabetes or thyroid disease may need attention before another pregnancy. Some womb conditions may lead to a discussion about surgery, and an inherited chromosome finding may lead to genetic counselling. The benefit of an operation depends on the condition; surgery for fibroids has not been shown clearly to reduce miscarriage risk.
RCOG finds no evidence that progesterone prevents recurrent miscarriage unless there is bleeding in early pregnancy. If you have bleeding in a new pregnancy, tell the clinician about your previous losses so they can assess whether progesterone is appropriate. Do not self-treat the bleeding.
When tests do not find a cause
Often, tests do not find a cause. RCOG says there is no current evidence that medical treatment reduces further miscarriage in unexplained cases. A future successful pregnancy remains possible, but your outlook depends on your age, previous losses and investigation results. Ask your clinician to explain what is still uncertain.
If you want another pregnancy, discuss a support plan before trying again: who to contact after a positive test, what scans may be offered and where to get help between appointments. You may also decide to pause or not try again.
Care now, and support with loss
Call 999 now (UK) or 911 (US), or your local emergency number, for heavy bleeding in pregnancy, or if pregnancy is possible and you have sudden severe tummy pain, shoulder-tip pain, marked weakness or fainting, even without vaginal bleeding. Contact your pregnancy unit or NHS 111 in the UK, your obstetric clinician in the US, or your local pregnancy service today for lighter bleeding or fluid leaking. A referral for investigations does not replace care for current symptoms.
Repeated loss can affect mental health, including anxiety, depression or post-traumatic stress. Book an appointment with your GP or doctor if you need support; a partner can ask for support too.
For urgent mental health support, call NHS 111 and select the mental health option in England, or contact your local urgent mental health service elsewhere. In the UK, you can call Samaritans on 116 123. In the US, call or text 988.
Call 999 now (UK) or 911 (US), or your local emergency number, if you cannot keep yourself safe or there is immediate danger to life.
When to get help
- Emergency
Call 999 now (UK) or 911 (US), or your local emergency number, for heavy bleeding in pregnancy, or if pregnancy is possible and you have sudden severe tummy pain, shoulder-tip pain, marked weakness or fainting, even without vaginal bleeding.
- Emergency
Call 999 now (UK) or 911 (US), or your local emergency number, if you cannot keep yourself safe or there is immediate danger to life.
- Same day
Contact your maternity or early pregnancy unit, or NHS 111 (UK), your obstetric clinician (US), or your local pregnancy service today for bleeding or fluid leaking during a current pregnancy.
- Book an appointment
Book a GP appointment (UK), or see your obstetric clinician (US and elsewhere), to discuss investigations and emotional support after repeated pregnancy losses.
Where you live
Services and advice differ between countries.
- UK
- RCOG uses three or more first trimester miscarriages, which need not be consecutive. Clinicians may investigate after two if they suspect an underlying cause.
- US
- ACOG uses two or more miscarriages and recommends a thorough examination and testing after two.
- Elsewhere
- Definitions and referral pathways differ. Ask your local clinician when investigation is appropriate rather than assuming the UK or US definition applies.
Sources
- Recurrent miscarriage, Royal College of Obstetricians and Gynaecologists No update date shown, checked
- Recurrent Miscarriage (Green-top Guideline No. 17), Royal College of Obstetricians and Gynaecologists Page updated , checked
- Repeated Miscarriages, American College of Obstetricians and Gynecologists Page updated , checked
- Miscarriage, NHS Page updated , checked
- Where to get urgent help for mental health, NHS Page updated , checked
- Talk to us on the phone, Samaritans No update date shown, checked
- Contact Us, 988 Suicide & Crisis Lifeline No update date shown, checked
- Ectopic Pregnancy, American College of Obstetricians and Gynecologists Page updated , checked